We thank all attendees for joining us at the 10th Modern Solid Phase Peptide Synthesis & Its Applications Symposium, which took place on Friday 24th and Saturday 25th October 2025 at the Hilton Fukuoka Sea Hawk in Fukuoka, Japan. 

Although the ‘Solid Phase’ Symposium is typically held in Australia, the 10th meeting marked only the second time it had been hosted in Japan, with the 4th meeting previously held in Kobe in 2013. This symposium showcased exciting advancements across all aspects of solid phase peptide synthesis, including innovations in solid supports, instrumentation, chemistries, and protocols. These breakthroughs enabled the synthesis of increasingly complex and large biological targets.

The 10th ‘Solid Phase’ Symposium offered an excellent opportunity to reconnect with colleagues and collaborators. We were honoured to welcome several world-renowned chemists and leading experts in peptides and proteins, whose talks inspired and informed. The stunning venue fostered dynamic discussions, networking, and the exchange of ideas. This event encouraged robust interaction between academic and commercial participants, often leading to fruitful collaborations and productive networks.

Topics of interest included, but were not limited to:

• Solid supports (resins), protecting groups, and synthesis strategies

• Microwave-enhanced solid phase peptide synthesis

• Peptide libraries, arrays, and combinatorial chemistry

• Peptidomimetics and cyclic peptides

• Cell- and blood-brain barrier-penetrating peptides and post-translational modifications (e.g., glycosylation)

• Challenges in “difficult sequences”

• Industrial-scale synthesis and commercialization

• Native chemical ligation and chip-based technologies

• Peptide-drug and peptide-PNA conjugates

• Nanotechnology, peptide therapy, and peptide delivery technologies (injectable, intranasal, and oral formulations)

We look forward to seeing you at our next symposium in 2027!

Craig Hutton, Yuji Nishiuchi, Akhter Hossain, Taku Yoshiya
Co-Chairs – 10th Modern Solid Phase Peptide Synthesis & Its Applications Symposium